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This article describes an inquiry lesson, recommended for grades 4-6, which explores Susan B. Anthony and Frederick Douglass’ 45 year relationship as allies, fighting for equal rights for African Americans and women during the 1800's. The lesson uses the National Council for the Social Studies (NCSS) Notable Trade Book for Young People award winner, Friends for Freedom: The Story of Susan B. Anthony & Frederick Douglass. Highlighted in the story line are the abolitionist movement, U.S. Civil War, Emancipation Proclamation, Susan’s famous 1872 arrest for voting, and the 13th, 15th, and 19th Amendments to the U.S. Constitution. Descriptions of historic equal rights challenges and successes, made possible through an unlikely partnership between two activists during the 1800's, extends students’ historic knowledge and skills through primary source analysis, interpreting characters and events, Socratic seminar, and monument and memorial study. The lesson’s central purpose is to help students actively examine historic U.S. equity issues and civil rights history.