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Faculty Research & Creative Activity
Document Type
Article
Publication Date
August 1987
Abstract
The acetogen Clostridium thermoautotrophicum was cultivated under CO-dependent chemolithotrophic conditions. CO-dependent growth profiles and energetics indicated that supplemental CO2 was fundamental to efficient growth at the expense of CO. Overall product stoichiometry approximated 6.5CO --> CH3CO2H + 3.5CO2 + 0.6 cell C + 0.5 unrecovered C. Initial CO/CO2 ratios of 2 to 4 yielded optimal doubling times and cell yields. Maximal YCO values approximated 2.5 g of cell dry weight per mol of CO consumed; Y H2 , was considerably lower than Y CO Cross-transfer growth experiments and protein profiles indicated differential expression of genes between CO and methanol cultures.
Recommended Citation
Savage, M.; Wu, Zhongren; Daniel, Steven; Lundie, Leon; and Drake, Harold, "Carbon Monoxide-Dependent Chemolithotrophic Growth of Clostridium thermoautotrophicum" (1987). Faculty Research & Creative Activity. 377.
https://thekeep.eiu.edu/bio_fac/377
https://works.bepress.com/steven_daniel/14/
Included in
Bacteriology Commons, Environmental Microbiology and Microbial Ecology Commons, Microbial Physiology Commons